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Distribution of Ventilation/Perfusion Ratios in Pulmonary intercalation: An add-on to the Interpretation of Ventilation/Perfusion Lung Scans Emmanuel Itti, MD; Severine Nguyen, MD; Fabrice Robin, MD; Serge Desarnaud, MD; Jean Rosso, MD; ´ Alain Harf, MD, PhD; and Michel Meignan, MD, PhD Department of Nuclear Medicine, Henri Mondor Hospital, Paris 12 University, Creteil, France ´ Diagnosis of pulmonary embolism (PE) by visual exposition of ventilation/perfusion (V/Q) scans is limited by the high percentages of patients classi?ed in the intermediate- and wiped out(p)- hazard categories. This study proposes a quantitative digest of the dispersal of V/Q ratios to better identify patients with PE. Methods: We studied 99 incidental patients who underwent dual-isotope 81mKr/99mTc-macroaggregate V/Q scanning and arterial blood gas analysis at heart 48 h. The 8-view V/Q scans were visually study by 2 observers according to the revised criteria of the Prospective investigatin g of Pulmonary Embolism Diagnosis (PIOPED) (normal scan or low, intermediate, or high probability of PE). Quantitative analysis of the posterior-view distribution histogram of V/Q ratios was performed using commit software.

Brie?y, regions of interest were drawn around the lungs on the matched V/Q images, sedate ?ltering was applied, normalized regional V/Q ratios were calculated at bottom each pixel, and a distribution histogram was built. Results: Patients with normal scans (n 16) had a prepotency of V/Q ratios (63.3% 13.0%) amongst 0.8 and 1.2. They had only 9.8% 5.8% of ratios 1.2, and the remaining 26.9% 7.5% of ratios were 0.8. By contrast, patients with PE (n 34) were characteriz ed by a signi? argot increase (15.5 10.0%, P! 0.04) in high V/Q ratios ( 1.2) and a signi?cant increase (34.5% 8.2%, P 0.003) in low V/Q ratios ( 0.8). Interestingly, a similar pattern was found in patients with a high PIOPED probability of PE, 21.3% 11.0% and 37.5% 9.2%, respectively. Within the nondiagnostic group...If you want to rifle a full essay, order it on our website: OrderEssay.net

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